66 year old with high grade fever and generalized weakness

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.This is an a online e log book to discuss our patient de-identified health data shared after taking his / her / guardians signed informed consent. Here we discuss our individual patients problems through series of inputs from available global online community of experts with an aim to solve those patients clinical problem with collective current best evident based input.
Maheshwari Jagathkari

Case report
 
A 66 year old daily labourer by occupation presented with chief complaints of high grade fever since 3 days and generalized weakness since 1 day.

Patient was apparently asymptomatic 3 days back when he went to some function and  then the next day he developed high grade fever insidious in onset that is associated with chills and rigors, intermittent type relived with medication without any diurnal variation.
Then the patient went to a local doctor where he was prescribed with some medication and his fever got relieved on taking medication.
Then he developed generalized weakness which is insidious in onset due to which he was unable to perform routine activity and was brought to our hospital.
H/O giddiness present since yesterda, H/O fall present (two times), H/O Loss of conciousness for 5 min
No H/O SOB, chest pain, palpitations
No H/O cough, cold, vomiting.

Daily routine
Patient wakes up at 6 am then gets freshened up, takes tea at 7 am eats breakfast at 8 am and then goes to work as a daily labourer and then comes back home at 1 pm takes lunch then sleeps for 2 hours then takes tea at 6 pm and eats dinner at 8 30 pm and goes to sleep by 9 30 pm.


Past history

K/c/o DM 2 since 20 years and is on regular medication since then.
When patient went to a local doctor his blood pressure was high and was told to take antihypertensive medication since 2 days.
Not a k/c/o asthma, epilepsy, CAD, CVA, thyroid disorders.

Patient is a known case of FILARIASIS of left lower limb and scrotum.

Personal history

He takes mixed diet with normal appetite and has regular bowel and bladder movements.
He takes alcohol daily since 1 year.

Family history

No significant family history

General examination

Pallor is present.
No features indicating the presence of icterus, cyanosis, clubbing, edema lymphadenopathy.
Fever chart



SYSTEMIC EXAMINATION

ABDOMINAL EXAMINATION
INSPECTION
No distention,No scars
Umbilicus - Inverted
Equal symmetrical movements in all the quadrants with respiration.
No visible pulsation,peristalsis, dilated veins and localized swellings.
PALPATION
No local rise of temperature, Abdomen is soft with no tenderness.
No spleenomegaly, hepatomegaly.
PERCUSSION
Liver span is 12cm, No hepatomegaly
Fluid thrill and shifting dullness absent.
No puddle sign.
AUSCULTATION
Bowel sounds present.


CVS- S1 and S2 heart sounds heard. 

RS- Bilateral air entry is present, normal vesicular breath sounds heard.

CNS EXAMINATION

Right Handed person, uneducated 

HIGHER MENTAL FUNCTIONS:

Conscious, oriented to time place and person.

MMSE 26/30

speech : muffled, unclear

Behavior : normal 

Memory : Intact.

Intelligence : Normal

Lobar Functions : Normal.

No hallucinations or delusions.

CRANIAL NERVE EXAMINATION:
Intact

MOTOR EXAMINATION:        
               Right Left
   
BULK UL Normal Normal
            LL Normal Normal

TONE UL  Normal  Normal
             LL Normal Normal

POWER UL 5/5 5/5 LL 5/5 5/5


REFLEXES
                           Right                   Left
BICEPS               +++                     +++
TRICEPS             ++                        ++
SUPINATOR        ++                        ++
KNEE                   +++                      +++
ANKLE                 ++                       ++
PLANTAR           flexor                  flexor




SENSORY EXAMINATION: intact

PROVISIONAL DIAGNOSIS

VIRAL PYREXIA 
DM 2 SINCE 20 YRS


INVESTIGATIONS

ECG

X-RAY CHEST
SEROLOGY
HBsAG- Positive
HIV, HCV- Negative



USG Abdomen

Grade 1 RPD changes in Left kidney
Left simple renal cortical cyst

CBP 6/6/23


HEMOGRAM 7/6/23


LFT 6/6/23


CUE 6/6/23

6/6/23
FBS- 70mg/dl
PLBS-167mg/dl

Blood urea-37mg/dl
Serum creatinine- 1.8mg/dl

Serum electrolytes-6/6/23

MRI DONE ON 10/6/23

Treatment

Inj.Monocef 1gm IV/BD
Inj.Doxycycline 200 mg iv/bd
Tab.Dolo 650mg PO/TID
Inj.Neomol 1gm IV/SOS if temp more than 101 F

Soap notes  
8/6/2023
AMC BED 5 - 66M


S:  
Fever spikes present 


O:
Patient is drowsy
BP: 130/80 mmHg
PR: 94 bpm
RR: 24 cpm.                             
Spo2: 98%                         
CVS: S1 s2 heard , no murmurs                    RS: B/L air entry present No added sounds 
CNS: No FND

A: 
Viral pyrexia ?Typhoid fever 
K/c/o DM 2 since 20 years


P: 
1)Inj.Monocef 1gm/IV/Bd (D2)
2)Inj.Doxycycline 200mg iv/bd
3)IV fluids NS@100ml/hr
4)Inj.Neomol 1gm/IV/SOS
5)Inj.HAI according to GRBS >200mg/dl
6)Tab.Dolo 650mg/PO/TID


Soap notes 
9/6/23 
AMC bed 5

S: 

Fever spikes present 

O: 

Pt is conscious, coherent and cooperative 
BP - 130/80 mmHg
PR- 80 bpm 
RR - 18 cpm 
Temp - 100 F
GRBS - 167 mg/dl 
SpO2 - 99% @RA
CVS - S1 S2 heard , no murmurs 
RS - BAE+ no added sounds 
P/A - soft and non tender 
CNS - no FND

A: 

PYREXIA ? TYPHOID FEVER K/C/O DM II SINCE 20 YEARS WITH HBsAg + 

P:

INJ. MONOCEF 1 G IV/BD
INJ.DOXYCYCLINE 200MG IV/BD
IV FLUIDS NS @ 100 ml/hr 
INJ NEOMOL 1 G IV/SOS
TAB DOLO 650 MG PO/TID
INJ HAI ACCORDING TO GRBS

Soap notes 
10/6/23 
AMC bed 5

S: 

Fever spikes present yesterday
Did not pass stools since 2 days 

O: 

Pt is drowsy
BP - 140/60 mmHg
PR- 97 bpm 
RR - 16 cpm 
Temp - 100 F
GRBS - 235/dl 
SpO2 - 98% @RA
CVS - S1 S2 heard , no murmurs 
RS - BAE+ no added sounds 
P/A - soft and non tender 
CNS - no FND

A: 

PYREXIA SECONDARY TO ? TYPHOID FEVER 
                                             ? MENINGITIS 
K/C/O DM II SINCE 20 YEARS WITH HBsAg +

P:

(D5) INJ. MONOCEF 1 G IV/BD
(D4) INJ DOXYCYCLINE 200 MG IV/BD
IV FLUIDS NS @ 100 ml/hr 
INJ NEOMOL 1 G IV/SOS
TAB DOLO 650 MG PO/TID
INJ HAI ACCORDING TO GRBS

Soap notes 
11/6/23 
AMC bed 5

S: 
 
Pt subjectively feeling better . 
Dysphagia has reduced 
Did not pass stools since 3 days 

O: 

Pt is drowsy
BP - 150/90 mmHg
PR- 80 bpm 
RR - 20 cpm 
Temp - 100 F
GRBS - 174/dl 
SpO2 - 98% @RA
CVS - S1 S2 heard , no murmurs 
RS - BAE+ no added sounds 
P/A - soft and non tender 
CNS - 

Tone 
 Rt UL Normal 
 Lt UL normal

Rt LL Normal
Lt LL hypotonic ? 

Power 
 Rt UL : 5/5
Lt UL : 5/5 

Rt LL : 5/5
Lt LL : - 

Reflexes   

         Rt Lt 

B ++ ++
T +++ ++
S + + 
K +++ ++
A - -
P Flexion flexion

A: 

PYREXIA SECONDARY TO ? TYPHOID FEVER 
                                             ? MENINGITIS 

K/C/O DM II SINCE 20 YEARS WITH HBsAg +

ACUTE INFARCT IN RIGHT FRONTAL LOBE ( PARASAGGITAL CORTEX ) ( ACA TERRITORY)

P:

(D6) INJ. MONOCEF 1 G IV/BD
(D5) INJ DOXYCYCLINE 200 MG IV/BD
IV FLUIDS NS @ 100 ml/hr 
INJ NEOMOL 1 G IV/SOS
TAB DOLO 650 MG PO/TID
TAB. AFORVOSTATIN + CLOPIDOGERL + ASPIRIN 20MG PO/HS /9PM
TAB. TENOGOVIR 300MG PO/OD ( ALTERNATE DAY --- NEXT DOSE (12/6/23)) 
INJ HAI ACCORDING TO GRBS

Soap notes 
12/6/23 
AMC bed 5

S: 
 
Pt subjectively feeling better . 
Generalized weakness resolving, no fever spikes 

O: 

Pt is c/c/c
BP - 150/90 mmHg
PR- 80 bpm 
RR - 20 cpm 
Temp - 100 F
GRBS - 256/dl 
SpO2 - 98% @RA
CVS - S1 S2 heard , no murmurs 
RS - BAE+ no added sounds 
P/A - soft and non tender 
CNS - HMF intact

Tone 
 Rt UL Normal 
 Lt UL normal

Rt LL Normal
Lt LL hypotonic ? 

Power 
 Rt UL : 5/5
Lt UL : 5/5 

Rt LL : 5/5
Lt LL : - 

Reflexes   

         Rt Lt 

B ++ ++
T +++ ++
S + + 
K +++ ++
A - -
P Flexion flexion

A: 

PYREXIA SECONDARY TO ? TYPHOID FEVER 
                                             ? MENINGITIS 

K/C/O DM II SINCE 20 YEARS WITH HBsAg +

ACUTE INFARCT IN RIGHT FRONTAL LOBE ( PARASAGGITAL CORTEX ) ( ACA TERRITORY)

P:

(D6) INJ. MONOCEF 1 G IV/BD
(D5) INJ DOXYCYCLINE 200 MG IV/BD
IV FLUIDS NS @ 100 ml/hr 
INJ NEOMOL 1 G IV/SOS
TAB DOLO 650 MG PO/TID
TAB. ATORVOSTATIN + CLOPIDOGERL + ASPIRIN 20MG PO/HS /9PM
TAB. TENOFOVIR 300MG PO/OD ( ALTERNATE DAY --- NEXT DOSE (13/6/23)) 
INJ HAI ACCORDING TO GRBS

Patient was discharged as he was getting better that is he was able to walk by himself.
Treatment at discharge
1)Inj.HAI 8 units SC/TID 8AM--2PM--9 PM
2)Tab.Atorvastatin+ Clopidogrel+Aspirin  20mg PO/HS/9PM
3)Tab.Tenofovir 300mg PO/OD
4)Tab.Amlong 5 mg PO/OD 
5)Tab.Dolo 650mg PO/SOS

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